Cotylenin a
WebFeb 1, 2015 · In the present study, we found that cotylenin A, a plant growth regulator and a potent inducer of differentiation in myeloid leukemia cells, significantly potentiated both ATO-induced inhibition of cell growth in a liquid culture, and ATO-induced inhibition of anchorage-independent growth in a semi-solid culture in human breast cancer MCF-7 … WebSep 29, 1997 · Cotylenins had been isolated as the plant-growth regulators, and have been found to affect a number of physiological processes of higher plants. Here we report that …
Cotylenin a
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WebSep 1, 2005 · A synthesis of versatile building blocks for these terpenoids is described, using as key steps ring closing metathesis reaction and Wagner - Meerwein rearrangement for cyclopenta[8]annulene rings system. Sesqui- and sesterterpenes of ophiobolin and fusicoccin families are important synthetic targets because of complexity of structure and … WebCotylenin-A (CN, Figure 1), discovered in 1970 by Sassa and co-workers in the culture filtrate of the fungus Cladosporium sp. 501-7W (genus and species unidentified), stimulates the growth of cotyledons of Chinese cabbage seedlings. 33 – 36 Intriguingly, the chemical structure and stereochemistry of the 5-8-5 fusicoccan diterpenoid scaffold ...
WebMar 19, 2024 · Cotylenin A (pictured) was originally isolated from a fungus. It is bioactive and can act as a plant growth regulator and an anti-cancer agent. While its absolute … WebMay 13, 2024 · An anticancer drug of fungal origin could be the way. Scientists at Waseda University succeeded in developing a method for a total synthesis of cotylenin A, a plant growth regulator which has ...
WebFeb 7, 2011 · Abstract. Fusicoccin A and cotylenin A are structurally related diterpene glucosides and show a phytohormone-like activity. However, only cotylenin A induces the differentiation of human myeloid leukemia cells. Since the cotylenin A producer lost its ability to proliferate during preservation, a study on the relationship between structure … WebCotylenin A, a plant growth regulator, and rapamycin, an inhibitor of mammalian target of rapamycin (mTOR), are potent inducers of differentiation of myeloid leukemia cells. …
WebMar 6, 2009 · Cotylenin A (Fig. 1 a) was originally identified as a cytokinin-like bioactive substance against plants produced by the fungus Cladosporium sp. 501-7W. 8 It was shown to have similar phytotoxic activity on tomato cuttings to the structural homologue fusicoccin A, a wilt-inducing phytotoxin isolated from the fungus Phomopsis amygdali (formerly …
WebThe active components, which we call cotylenin A and B, have been isolated, and some of their physical properties determined. WE have found substances in the culture filtrate of a fungus, strain ... pedicures bowling green kyWebJun 10, 2016 · Cotylenin A (CN-A, plant growth regulator) combined with PEITC in the treatment of pancreatic cancer can synergistically induce ROS production and lead to cell death mainly due to the induction of ... meaning of throne in hindiWebCotylenin A C33H50O11 CID 5477444 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. pedicures for kids austin txWebJul 1, 2003 · Abstract. Cotylenin A, a novel inducer of the differentiation of leukemia cells, and IFN-α synergistically inhibited the growth of and induced apoptosis in several human … meaning of throes of passionWebAug 14, 2008 · Cotylenin A, a plant growth regulator, and rapamycin, an inhibitor of mammalian target of rapamycin (mTOR), are potent inducers of differentiation of myeloid … pedicures for guys near meWebJul 1, 2008 · Cotylenin A or IPA immediately induced the expression of S100P mRNA and protein, and the differentiation of HL-60 cells was suppressed by treatment with antisense oligonucleotides against S100P, which suggests that S100P plays an important role in cell differentiation [28]. Cotylenin A enhanced the LCA acetate-induced differentiation … pedicures for men in kingsport tnWebMar 14, 2016 · With the aid of computational predictions, experimental validation, and biosynthetic logic-based strategies, Zhang and co-workers first rectified the conclusion that all brassicicenes were ... meaning of throat slit