Splet30. mar. 2024 · PDGF-BB had much weaker effects on 32D/PDGF-β R cell differentiation, suggesting that increased PKC-δ expression enhanced monocytic differentiation. These results indicate that PKC-δ is a downstream molecule in the PDGFR signaling pathway and may play a pivotal role in PDGF-β R-mediated cell differentiation. SpletThe PDGFR pathway is discussed in greater depth (14). PDGF polypeptide chains consist of four different types, each of which is encoded by four different genes. PDGF-B was the first of these four genes, which was elucidated via amino acid sequencing, which revealed its surprising similarity to the simian sarcoma virus (17).
Activation of PDGF pathway links LMNA mutation to dilated
Splet21. mar. 2024 · PDGFB (Platelet Derived Growth Factor Subunit B) is a Protein Coding gene. Diseases associated with PDGFB include Dermatofibrosarcoma Protuberans and Basal Ganglia Calcification, Idiopathic, 5 . Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and GPCR Pathway . SpletSchmahl, J., Rizzolo, K., & Soriano, P. (2008). The PDGF signaling pathway controls multiple steroid-producing lineages. Genes & Development, 22(23), 3255–3267. doi ... oxley lighting
Comprehensive dissection of PDGF-PDGFR signaling pathways in …
Splet17. mar. 2024 · Using pharmacological inhibitors, we dissected distinct aspects of the PDGF-BB response that are controlled by extracellular signal-regulated kinase (ERK) and … SpletPDGFR-beta signaling pathway: Full description or abstract : Collection: C2: Curated CP: Canonical Pathways CP:PID: PID Pathways: Source publication: Pubmed ... Pathway Interaction Database (NCI, NIH and Nature Publishing Group) Source platform or identifier namespace: Human_UniProt_ID: SpletN00231 TGFA-EGFR-PI3K signaling pathway N00039 PDGF-PDGFR-PI3K signaling pathway N00045 KITLG-KIT-PI3K signaling pathway N00037 FGF-FGFR-PI3K signaling pathway N00234 IGF2-IGF1R-PI3K signaling pathway N00043 HGF-MET-PI3K signaling pathway N00220 PTEN-PIP3-AKT signaling pathway N00218 FLT3LG-FLT3-RAS-PI3K signaling … jefferson county personal property taxes