WebReproductive toxicity refers to the potential risk from a given chemical, physical or biologic agent to adversely affect both male and female fertility as well as offspring development. … WebArticle 58(1) of the REACH Regulation to include substances referred to in Article 57 in Annex XIV to the REACH Regulation. (2) Article 58(3) of the REACH Regulation requires ECHA to make further ... Toxic for reproduction (Article 57c) Date of inclusion in Annex XIV plus at least 36 months (1)) Latest application date plus 18 months (1)) None ...
ECHA Website
WebJan 25, 2024 · Toxic for reproduction (Article 57 c) Solvent/extraction agent. Dioctyltin dilaurate, stannane, dioctyl-, bis(coco acyloxy) derivs., and any other stannane, dioctyl-, … WebCarcinogens, Mutagens and Reprotoxic chemicals CMRs are substances that are carcinogenic, mutagenic, or toxic to reproduction. In other words, they have inherent properties that can cause cancer, alter DNA or damage reproductive systems. These properties correspond to article 57 a-c of REACH. pet friendly holiday resorts
CHMP Scientific Article 5(3) Opinion on: The Potential Risks of …
WebA substance should therefore be added to Annex I of Directive 67/548/EEC if it meets the criteria for classification as carcinogenic, mutagenic or toxic for reproduction categories … WebToxic for reproduction (Article 57c);PBT (Article 57d);vPvB (Article 57e);Equivalent level of concern having probable serious effects to human health (Article 57 (f) - human health);Equivalent level of concern having probable serious effects to the environment (Article 57 (f) - environment) Compulsory fields are marked with an asterisk ( * ) WebSalbutamol is a relatively selective beta 2-adrenoreceptor stimulant with rapid, potent bronchodilator activity and only minor inotropic or chronotropic effects. It was not found to be mutagenic. LD50 values and other acute studies indicated low toxicity. Findings published for repeat dose studies were mainly uneventful. star trek attack wing micro machines